HitPredict

Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 845 Hs			1 450
+	Hs
		428001 VAV_HUMAN (1-845): 0: 641: 100.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		548681 VAV_HUMAN (1-845): 0: 641: 100.00		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		381112 VAV_HUMAN (1-845): 0: 641: 100.00		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		381242 NGEF_HUMAN (44-525): 4.65e-71: 250: 17.09		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		1037227 ARHG7_HUMAN (756-843): 5.34e-15: 81.4: 27.27		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		924548 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		381204 ARHG7_HUMAN (756-843): 5.34e-15: 81.4: 27.27		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		428131 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		924460 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		924836 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB6_HUMAN (1-446): 0: 700: 92.38