HitPredict

Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 845 Hs			1 1117
+	Hs
		1148973 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		CYTSA_HUMAN (1-1117): 1.12e-71: 262: 100.00
+	Hs
		1129137 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Mm
		57840 KALRN_MOUSE (140-667): 2.18e-64: 238: 16.52		CYTSA_MOUSE (1-1117): 2.31e-66: 246: 95.17
+	Hs
		993295 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		ACTN3_HUMAN (1009-1115): 7.86e-51: 196: 40.74
+	Hs
		521615 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		70405 PKHG2_HUMAN (163-508): 3.29e-74: 266: 24.52		B2R8Y4_HUMAN (1009-1115): 7.86e-51: 196: 40.74
+	Hs
		993294 PKHG2_HUMAN (163-508): 3.29e-74: 266: 24.52		ACTN3_HUMAN (1009-1115): 7.86e-51: 196: 40.74
+	Hs
		725699 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		211665 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		50564 PKHG3_HUMAN (183-669): 1.25e-79: 281: 20.81		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725023 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725246 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Hs
		1356647 PKHG1_HUMAN (113-773): 9.19e-79: 280: 15.51		MYH13_HUMAN (278-1070): 1.15e-29: 130: 10.89
+	Hs
		728517 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		MYH11_HUMAN (342-1028): 7.19e-25: 114: 9.72
+	Hs
		506843 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		SPTB1_HUMAN (1012-1115): 7.3e-16: 85.5: 47.62
+	Ce
		110517 SEM5_CAEEL (617-837): 4.22e-17: 83.2: 27.68		H2L2C8_CAEEL (1009-1116): 1.45e-49: 192: 43.12
+	Hs
		521521 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Ce
		666217 SEM5_CAEEL (617-837): 4.22e-17: 83.2: 27.68		Q23158_CAEEL (1009-1116): 1.02e-46: 184: 40.37
+	Hs
		211557 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		724756 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77