HitPredict

Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	31980649, 8530437, unassigned2173
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 845 Hs			1 451
+	Hs
		548680 VAV_HUMAN (1-845): 0: 641: 100.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		548725 VAV_HUMAN (1-845): 0: 641: 100.00		TBA3E_HUMAN (1-440): 0: 698: 97.05
+	Hs
		428001 VAV_HUMAN (1-845): 0: 641: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		548681 VAV_HUMAN (1-845): 0: 641: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		1175184 ECT2_HUMAN (83-631): 2.68e-76: 268: 16.55		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		924827 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		924459 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		924458 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428131 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		924460 GRB2_HUMAN (787-838): 7.33e-15: 76.3: 48.08		TBB4B_HUMAN (1-437): 0: 693: 40.50