Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: PTN22 (Q9Y2R2)
Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP) (PEST-domain phosphatase) (PEP)
Gene: PTPN22

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 16461343
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Y_phosphatase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030217 - T cell differentiation
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 845
Hs

1 807
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024