HitPredict

Interactor 1: ELN (P15502)
Elastin (Tropoelastin)
Gene: ELN

Interactor 2: LYOX (P28300)
Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase) [Cleaved into: Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form]
Gene: LOX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	12686141, 19570982, 30082873
Identification Methods	pull down, enzyme linked immunosorbent assay, surface plasmon resonance
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 417
+	Hs
		358633 CO3A1_HUMAN (25-623): 4.22e-24: 111: 20.17		LYOX_HUMAN (1-417): 0: 746: 100.00
+	Hs
		358482 CO1A1_HUMAN (1-458): 2.46e-20: 99.1: 17.73		LYOX_HUMAN (1-417): 0: 746: 100.00
+	Bt
		392872 ELN_BOVIN (121-786): 2.19e-31: 133: 56.11		LYOX_BOVIN (1-417): 0: 712: 89.98
+	Hs
		436014 CO1A2_HUMAN (531-785): 2.01e-13: 76.3: 18.39		LYOX_HUMAN (1-417): 0: 746: 100.00
+	Bt
		392873 ELN_BOVIN (121-786): 2.19e-31: 133: 56.11		LOXL1_BOVIN (149-414): 1.3e-135: 402: 62.09