HitPredict

Interactor 1: ELN (P15502)
Elastin (Tropoelastin)
Gene: ELN

Interactor 2: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	10825173, 19570982
Identification Methods	pull down, surface plasmon resonance, enzyme linked immunosorbent assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005201 - extracellular matrix structural constituent GO:0005576 - extracellular region GO:0030023 - extracellular matrix constituent conferring elasticity GO:0031012 - extracellular matrix GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 2871
+	Hs
		548782 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBN2_HUMAN (1-1616): 3.07e-108: 391: 24.75
+	Hs
		804242 CO4A6_HUMAN (255-783): 1.12e-30: 132: 16.85		NOTC1_HUMAN (1-864): 9.28e-54: 212: 16.43
+	Hs
		548778 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBLN1_HUMAN (224-363): 4.15e-12: 73.9: 34.75
+	Hs
		548784 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBLN2_HUMAN (224-363): 3.4e-10: 68.2: 34.04
+	Hs
		126331 CO1A1_HUMAN (1-458): 2.46e-20: 99.1: 17.73		MATN2_HUMAN (36-405): 2.73e-21: 104: 17.73
+	Dm
		113976 M9PB30_DROME (206-645): 2.56e-15: 83.1: 14.29		M9PB30_DROME (4-552): 2.11e-09: 65.8: 9.46
+	Hs
		596152 CO5A1_HUMAN (381-786): 5.16e-12: 72.1: 15.53		TENA_HUMAN (2577-2752): 7.66e-10: 67.4: 15.49