Interactor 1: MCP (P15529)
Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46)
Gene: CD46

Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 17699108
Identification Methods electrophoretic mobility supershift assay, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0010628 - positive regulation of gene expression
GO:0010629 - negative regulation of gene expression
GO:0032733 - positive regulation of interleukin-10 production
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 392
Hs

1 770
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024