HitPredict

Interactor 1: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Interactor 2: NOC4 (Q06512)
Nucleolar complex protein 4 (U three protein 19) (U3 small nucleolar RNA-associated protein 19) (U3 snoRNA-associated protein 19)
Gene: NOC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	12150911, 16429126, 28244370, 29361028, 35385737, 32943521
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 327 Sc			1 552
+	Hs
		603681 FBRL_HUMAN (81-320): 8.6e-149: 422: 70.00		NOC4L_HUMAN (7-533): 1.27e-135: 405: 27.68
+	Hs
		603613 FBRL_HUMAN (81-320): 8.6e-149: 422: 70.00		NOC3L_HUMAN (27-549): 7.06e-103: 329: 13.66
+	Sc
		549527 FBRL_YEAST (85-327): 7.99e-147: 418: 100.00		MAK21_YEAST (30-518): 2.26e-90: 301: 13.87
+	Hs
		603461 FBRL_HUMAN (81-320): 8.6e-149: 422: 70.00		CEBPZ_HUMAN (18-548): 1.65e-86: 290: 12.89