Interactor 1: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Interactor 2: NOP58 (Q12499)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 9372940, 16554755, 25060708, 31756331, 12068309, 12150911, 16429126, 18268104, 18631361, 35385737, 37968396, 21558325, 22995916, 14759368, 23267104
Identification Methods affinity chromatography technology, two hybrid, miniaturized immunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Fibrillarin~Nop, Fibrillarin~NOP5NT
Common GO terms GO:0000452 - snoRNA guided rRNA 2'-O-methylation
GO:0000494 - box C/D sno(s)RNA 3'-end processing
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 327
Sc

1 511
+ Hs
+ Hs
+ Ca
+ Sc
+ Ce
+ Pf
+ Ss
+ Af

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Last updated: 15 Jul 2024