Interactor 1: UBC4 (P15731)
Ubiquitin-conjugating enzyme E2 4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein 4) (Ubiquitin-protein ligase 4)
Gene: UBC4

Interactor 2: NOT4 (P34909)
General negative regulator of transcription subunit 4 (EC 2.3.2.27) (Modulator of transcription 2)
Gene: MOT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 16554755, 16926149, 37968396, 25914052, 15001359, 19346402, 22243599, 22421358
Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_4
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006513 - protein monoubiquitination
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 148
Sc

1 587
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Last updated: 15 Jul 2024