HitPredict

Interactor 1: UBC4 (P15731)
Ubiquitin-conjugating enzyme E2 4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein 4) (Ubiquitin-protein ligase 4)
Gene: UBC4

Interactor 2: CDH1 (P53197)
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)
Gene: CDH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	17178718, 37774018, 22072716
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 148 Sc			1 566
+	Hs
		849488 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		FZR1_HUMAN (30-566): 8.72e-96: 302: 36.58
+	Hs
		895954 UB2D3_HUMAN (2-148): 4.59e-81: 236: 78.91		FZR1_HUMAN (30-566): 8.72e-96: 302: 36.58
+	Hs
		245581 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		TBL1X_HUMAN (26-559): 8.64e-82: 268: 12.79
+	Hs
		849435 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		TBL1R_HUMAN (242-559): 5.76e-82: 267: 18.66
+	Hs
		245625 UB2E3_HUMAN (2-147): 2.67e-75: 224: 64.38		TBL1X_HUMAN (26-559): 8.64e-82: 268: 12.79
+	Hs
		1282344 UB2E3_HUMAN (2-147): 2.67e-75: 224: 64.38		TBL1R_HUMAN (242-559): 5.76e-82: 267: 18.66
+	Hs
		896507 UBE2N_HUMAN (4-148): 7.89e-70: 208: 46.90		FBXW7_HUMAN (154-496): 7.07e-75: 253: 17.00
+	Hs
		921784 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		849304 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		919704 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		895772 UB2D3_HUMAN (2-148): 4.59e-81: 236: 78.91		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Dm
		218245 UBCD1_DROME (2-148): 1.08e-81: 238: 79.59		O44382_DROME (320-562): 3.01e-12: 70.9: 26.02