HitPredict

Interactor 1: UBC5 (P15732)
Ubiquitin-conjugating enzyme E2-16 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: UBC5

Interactor 2: APC11 (Q12157)
Anaphase-promoting complex subunit 11 (EC 6.3.2.-)
Gene: APC11

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17632060
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-ANAPC11
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 148 Sc			1 165
+	Sc
		549847 UBC4_YEAST (1-148): 3.78e-81: 237: 92.57		APC11_YEAST (1-165): 1.27e-93: 270: 100.00
+	Hs
		849463 UB2D1_HUMAN (2-148): 6.69e-81: 236: 78.91		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		919882 UB2D2_HUMAN (2-148): 1.51e-80: 235: 78.91		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		895932 UB2D3_HUMAN (2-148): 1.98e-79: 233: 78.91		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		921482 UB2D4_HUMAN (2-148): 1.42e-81: 238: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Sp
		804461 UBC4_SCHPO (2-148): 6.62e-79: 231: 81.63		APC11_SCHPO (1-101): 1.32e-32: 113: 45.55
+	Hs
		849303 UB2D1_HUMAN (2-148): 6.69e-81: 236: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		895979 UB2D1_MOUSE (2-148): 6.69e-81: 236: 78.91		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Hs
		919703 UB2D2_HUMAN (2-148): 1.51e-80: 235: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		919923 UB2D2_MOUSE (2-148): 1.51e-80: 235: 78.91		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Ce
		715108 UBC2_CAEEL (2-148): 1.17e-80: 236: 78.91		APC11_CAEEL (1-102): 6.48e-29: 105: 36.54
+	Ce
		715111 UBC2_CAEEL (2-148): 1.17e-80: 236: 78.91		RBX1_CAEEL (2-102): 2.7e-29: 105: 27.36
+	Hs
		895771 UB2D3_HUMAN (2-148): 1.98e-79: 233: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		895973 UB2D3_MOUSE (2-148): 1.98e-79: 233: 78.91		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Sc
		549843 UBC4_YEAST (1-148): 3.78e-81: 237: 92.57		RBX1_YEAST (2-102): 9.21e-26: 96.8: 27.36
+	Sc
		549867 UBC5_YEAST (1-148): 1.51e-80: 235: 100.00		RBX1_YEAST (2-102): 9.21e-26: 96.8: 27.36
+	Hs
		1354003 UB2D4_HUMAN (2-148): 1.42e-81: 238: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		849472 UB2D1_HUMAN (2-148): 6.69e-81: 236: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		919890 UB2D2_HUMAN (2-148): 1.51e-80: 235: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		895936 UB2D3_HUMAN (2-148): 1.98e-79: 233: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51