HitPredict

Interactor 1: PHKG2 (P15735)
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)
Gene: PHKG2

Interactor 2: KPBB (Q93100)
Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)
Gene: PHKB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	26496610, 28514442, 33961781, 35271311, 32707033, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005829 - cytosol GO:0005964 - phosphorylase kinase complex GO:0005977 - glycogen metabolic process GO:0006091 - generation of precursor metabolites and energy
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1093
+	Hs
		1039138 KCC2D_HUMAN (20-306): 5.49e-63: 212: 39.86		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Hs
		1039011 KCC2G_HUMAN (15-306): 1.31e-61: 209: 39.39		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Hs
		1038910 KCC2B_HUMAN (20-306): 1.99e-59: 206: 39.86		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Dm
		1280589 Q961E7_DROME (1-389): 8.64e-134: 391: 50.60		KPBB_DROME (29-1088): 0: 1509: 46.88
+	Dm
		1280594 Q961E7_DROME (1-389): 8.64e-134: 391: 50.60		KPBA_DROME (691-1077): 1.16e-144: 468: 28.45
+	Hs
		549877 PHKG2_HUMAN (1-406): 2.84e-153: 440: 100.00		KPB2_HUMAN (912-1086): 1.14e-58: 223: 35.36
+	Hs
		549878 PHKG2_HUMAN (1-406): 2.84e-153: 440: 100.00		KPB1_HUMAN (930-1079): 5.73e-52: 201: 32.48
+	Hs
		801516 PHKG1_HUMAN (5-389): 4.4e-139: 403: 62.44		KPB2_HUMAN (912-1086): 1.14e-58: 223: 35.36