HitPredict

Interactor 1: KCC2D (P15791)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: Camk2d

Interactor 2: NMDE1 (Q00959)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12147342
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006816 - calcium ion transport GO:0043005 - neuron projection
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 533 Rn			1 1464
+	Rn
		506718 KCC2A_RAT (1-511): 0: 551: 80.82		NMDE1_RAT (1-1464): 0: 1774: 100.00
+	Rn
		550161 KCC2D_RAT (1-533): 0: 643: 100.00		NMDE2_RAT (4-1464): 0: 1522: 52.85
+	Mm
		659449 KCC2B_MOUSE (1-512): 0: 576: 77.31		NMDE2_MOUSE (4-1464): 0: 1514: 52.72
+	Rn
		506719 KCC2A_RAT (1-511): 0: 551: 80.82		NMDE2_RAT (4-1464): 0: 1522: 52.85
+	Mm
		515226 KCC2A_MOUSE (1-511): 0: 551: 80.82		NMDE2_MOUSE (4-1464): 0: 1514: 52.72
+	Hs
		1028136 KCC2G_HUMAN (1-512): 0: 554: 77.06		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Hs
		1028155 KCC2A_HUMAN (1-511): 0: 551: 80.82		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Mm
		659444 KCC2B_MOUSE (1-512): 0: 576: 77.31		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Rn
		506693 KCC2A_RAT (1-511): 0: 551: 80.82		GRIA1_RAT (13-912): 0: 695: 19.50
+	Hs
		786716 KCC2A_HUMAN (1-511): 0: 551: 80.82		GRIA1_HUMAN (13-912): 0: 689: 19.60
+	Rn
		514948 KCC2G_RAT (1-512): 0: 567: 78.94		GRIA4_RAT (10-863): 0: 662: 18.82
+	Mm
		515217 KCC2A_MOUSE (1-511): 0: 551: 80.82		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Hs
		984259 KCC2G_HUMAN (1-512): 0: 554: 77.06		NMDZ1_HUMAN (13-940): 0: 674: 23.07
+	Hs
		984288 KCC2A_HUMAN (1-511): 0: 551: 80.82		NMDZ1_HUMAN (13-940): 0: 674: 23.07
+	Hs
		816227 KCC2A_HUMAN (1-511): 0: 551: 80.82		GRIA4_HUMAN (15-863): 0: 665: 19.23