HitPredict

Interactor 1: TFE2 (P15806)
Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1)
Gene: Tcf3

Interactor 2: ID1 (P20067)
DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1)
Gene: ID1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	11591653
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 651 Mm			1 168
+	Mm
		550218 TFE2_MOUSE (1-651): 0: 901: 100.00		Q6GTZ3_MOUSE (1-135): 7.96e-69: 207: 100.00
+	Hs
		551478 TFE2_HUMAN (2-651): 0: 854: 80.52		ID1_HUMAN (14-135): 7.51e-63: 192: 89.84
+	Mm
		550183 TFE2_MOUSE (1-651): 0: 901: 100.00		ID3_MOUSE (17-121): 4.09e-42: 138: 44.76
+	Mm
		550184 TFE2_MOUSE (1-651): 0: 901: 100.00		ID2_MOUSE (17-139): 6.46e-42: 138: 44.62
+	Rn
		600264 TFE2_RAT (1-651): 0: 899: 95.08		ID3_RAT (17-121): 1.65e-42: 139: 45.71
+	Hs
		551503 TFE2_HUMAN (2-651): 0: 854: 80.52		ID3_HUMAN (17-121): 3.92e-42: 138: 45.71
+	Hs
		551502 TFE2_HUMAN (2-651): 0: 854: 80.52		ID2_HUMAN (17-139): 1.08e-41: 137: 45.39
+	Hs
		551480 TFE2_HUMAN (2-651): 0: 854: 80.52		ID4_HUMAN (61-128): 3.28e-23: 91.3: 50.00
+	Mm
		1142448 HTF4_MOUSE (1-651): 0: 721: 46.95		Q6GTZ3_MOUSE (1-135): 7.96e-69: 207: 100.00
+	Mm
		1141284 ITF2_MOUSE (2-651): 0: 710: 48.13		Q6GTZ3_MOUSE (1-135): 7.96e-69: 207: 100.00
+	Hs
		780982 HTF4_HUMAN (1-651): 0: 719: 48.71		ID1_HUMAN (14-135): 7.51e-63: 192: 89.84
+	Hs
		551084 ITF2_HUMAN (2-651): 0: 702: 47.83		ID1_HUMAN (14-135): 7.51e-63: 192: 89.84
+	Mm
		780945 HTF4_MOUSE (1-651): 0: 721: 46.95		ID3_MOUSE (17-121): 4.09e-42: 138: 44.76
+	Mm
		781007 HTF4_MOUSE (1-651): 0: 721: 46.95		ID2_MOUSE (17-139): 6.46e-42: 138: 44.62
+	Hs
		971137 HTF4_HUMAN (1-651): 0: 719: 48.71		ID3_HUMAN (17-121): 3.92e-42: 138: 45.71
+	Hs
		970599 HTF4_HUMAN (1-651): 0: 719: 48.71		ID2_HUMAN (17-139): 1.08e-41: 137: 45.39
+	Mm
		780944 ITF2_MOUSE (2-651): 0: 710: 48.13		ID3_MOUSE (17-121): 4.09e-42: 138: 44.76
+	Mm
		781006 ITF2_MOUSE (2-651): 0: 710: 48.13		ID2_MOUSE (17-139): 6.46e-42: 138: 44.62
+	Hs
		814913 HTF4_HUMAN (1-651): 0: 719: 48.71		ID4_HUMAN (61-128): 3.28e-23: 91.3: 50.00
+	Hs
		551089 ITF2_HUMAN (2-651): 0: 702: 47.83		ID4_HUMAN (61-128): 3.28e-23: 91.3: 50.00