HitPredict

Interactor 1: ZEP1 (P15822)
Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)
Gene: HIVEP1

Interactor 2: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2718 Hs			1 406
+	Hs
		550441 ZEP1_HUMAN (2-2718): 0: 801: 100.00		LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95
+	Hs
		550422 ZEP1_HUMAN (2-2718): 0: 801: 100.00		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Hs
		550345 ZEP1_HUMAN (2-2718): 0: 801: 100.00		LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84
+	Hs
		550446 ZEP1_HUMAN (2-2718): 0: 801: 100.00		LHX6_HUMAN (2-259): 1.04e-44: 160: 30.77
+	Ce
		589696 SMA9_CAEEL (401-517): 2.85e-21: 105: 30.25		LIN11_CAEEL (2-324): 2.02e-56: 192: 42.11
+	Hs
		846679 ZNF84_HUMAN (684-1016): 3.15e-26: 119: 7.72		LMO3_HUMAN (4-121): 4.42e-51: 169: 36.59
+	Ce
		447562 SMA9_CAEEL (401-517): 2.85e-21: 105: 30.25		MEC3_CAEEL (2-257): 8.94e-47: 164: 35.45
+	Hs
		1033698 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Dm
		114756 Q8MRU2_DROME (241-471): 5.49e-12: 73.3: 13.98		M9PD53_DROME (1-376): 7.91e-55: 191: 31.10
+	Dm
		112556 Q9VM37_DROME (381-551): 2.98e-11: 71.1: 22.65		M9NCY1_DROME (1-376): 1.87e-55: 189: 31.10
+	Hs
		196621 ZBT24_HUMAN (2008-2475): 6.03e-14: 79.9: 15.43		LHX8_HUMAN (3-307): 2.36e-45: 162: 27.36
+	Hs
		1033682 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		LMO3_HUMAN (4-121): 4.42e-51: 169: 36.59
+	Hs
		638487 ZNF84_HUMAN (684-1016): 3.15e-26: 119: 7.72		RBTN1_HUMAN (3-57): 2.28e-10: 60.7: 22.41
+	Hs
		638500 ZN177_HUMAN (1996-2157): 1.8e-22: 106: 15.43		RBTN1_HUMAN (3-57): 2.28e-10: 60.7: 22.41
+	Hs
		638501 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		RBTN1_HUMAN (3-57): 2.28e-10: 60.7: 22.41
+	Hs
		638592 IKZF3_HUMAN (358-457): 1.52e-11: 71.9: 35.00		RBTN1_HUMAN (3-57): 2.28e-10: 60.7: 22.41