HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36950384
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 2581
+	Hs
		620600 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		550249 PABP1_HUMAN (1-636): 0: 571: 100.00		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		550289 PABP1_HUMAN (1-636): 0: 571: 100.00		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1088320 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1101959 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		620329 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		620371 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		243537 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		SMCA5_HUMAN (695-1722): 0: 901: 26.43
+	Hs
		550308 PABP1_HUMAN (1-636): 0: 571: 100.00		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62
+	Hs
		1101977 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62
+	Hs
		620216 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		SMCA4_HUMAN (69-1478): 0: 816: 23.14