HitPredict

Interactor 1: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Interactor 2: RAD5 (P32849)
DNA repair protein RAD5 (EC 3.6.4.-) (Radiation sensitivity protein 5) (Revertibility protein 2)
Gene: RAD5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	16224103, 25690888, 31281030, 19706603, 35338218, 12226657, 29396601, 34990655, 19851286
Identification Methods	two hybrid, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0006301 - postreplication repair GO:0070987 - error-free translesion synthesis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 258 Sc			1 1169
+	At
		1324854 PCNA1_ARATH (1-258): 1e-106: 311: 40.15		SM3L2_ARATH (151-1168): 0: 620: 27.59
+	At
		1324855 PCNA2_ARATH (1-258): 4.46e-105: 306: 39.77		SM3L2_ARATH (151-1168): 0: 620: 27.59
+	Hs
		517257 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		HLTF_HUMAN (159-1169): 1.62e-176: 548: 21.23
+	Hs
		517123 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		ATRX_HUMAN (14-1168): 5.83e-139: 468: 13.47
+	Sc
		550580 PCNA_YEAST (1-258): 5.31e-95: 281: 100.00		ULS1_YEAST (104-1168): 2.18e-152: 498: 20.07
+	Hs
		238261 RAD1_HUMAN (2-258): 1.09e-64: 204: 15.87		ATRX_HUMAN (14-1168): 5.83e-139: 468: 13.47
+	Mm
		572258 PCNA_MOUSE (1-258): 5.1e-111: 322: 35.52		SMCA5_MOUSE (991-1167): 8.21e-62: 231: 31.32
+	Hs
		517262 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		SHPRH_HUMAN (581-845): 2.01e-17: 90.5: 26.83
+	Hs
		517468 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		SMRCD_HUMAN (528-874): 1.34e-09: 64.7: 24.65