HitPredict

Interactor 1: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Interactor 2: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	12226657, 18155241, 18701921, 23034805, 23712011
Identification Methods	two hybrid, enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PCNA_C~UQ_con
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 258 Sc			1 157
+	Dm
		572185 PCNA_DROME (1-258): 7.5e-110: 318: 35.91		Q7KNM2_DROME (1-156): 5.99e-73: 217: 53.85
+	Hs
		517161 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	At
		1114992 PCNA1_ARATH (1-258): 1e-106: 311: 40.15		SCE1_ARATH (2-155): 7.8e-73: 216: 59.74
+	Hs
		517183 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41
+	Hs
		517129 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		UBE2A_HUMAN (1-154): 1.04e-66: 201: 38.96
+	Hs
		517180 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		UBE2B_HUMAN (1-154): 4.86e-66: 199: 38.31
+	Zm
		74431 Q9SAQ3_MAIZE (1-258): 6.6e-102: 298: 39.38		B4FCQ9_MAIZE (4-156): 1.24e-73: 218: 33.33
+	Dm
		1181396 Q868I9_DROME (1-36): 9.18e-09: 52: 36.11		Q7KNM2_DROME (1-156): 5.99e-73: 217: 53.85