HitPredict

Interactor 1: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.883

Property	Details
Experiments	18719252, 15590687, 23034805, 22382979
Identification Methods	two hybrid, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PCNA_C~Rad60-SLD
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 258 Sc			1 101
+	Dm
		332492 PCNA_DROME (1-258): 7.5e-110: 318: 35.91		O97102_DROME (13-99): 2.66e-35: 117: 43.18
+	Hs
		517181 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	At
		1324253 PCNA1_ARATH (1-258): 1e-106: 311: 40.15		SUMO3_ARATH (9-98): 4.23e-33: 112: 37.36
+	At
		879016 PCNA1_ARATH (1-258): 1e-106: 311: 40.15		SUMO1_ARATH (11-96): 1.49e-32: 110: 45.98