Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: PAF15 (Q15004)
PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor)
Gene: PCLAF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 21700221, 11313979, 36734974, 16288740, 21628590, 26186194, 26496610, 28514442, 32296183, 33961781, 28524877, 24958773, unassigned1304
Identification Methods pull down, affinity chromatography technology, two hybrid, cross-linking study, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAF~PCNA_C, PAF~PCNA_N
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0019985 - translesion synthesis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 261
Hs

1 111
+ Xl

Service provided by Combinatics, Japan

Last updated: 11Aug2025