HitPredict

Interactor 1: ABP1 (P15891)
Actin-binding protein
Gene: ABP1

Interactor 2: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	11331312, 30042427
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0030479 - actin cortical patch GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Sc			1 391
+	Hs
		282322 NEBL_HUMAN (9-592): 3.79e-62: 223: 13.70		ACTB_HUMAN (2-389): 0: 566: 46.39
+	Sc
		551386 ABP1_YEAST (1-592): 2.89e-65: 225: 100.00		ACT_YEAST (1-389): 0: 557: 44.87
+	Hs
		891799 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTB_HUMAN (2-389): 0: 566: 46.39
+	Hs
		929879 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTG_HUMAN (2-389): 0: 566: 46.13
+	Hs
		596202 NEBU_HUMAN (64-591): 6.24e-45: 174: 15.20		ACTB_HUMAN (2-389): 0: 566: 46.39
+	Hs
		932187 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTC_HUMAN (2-389): 0: 559: 45.88
+	Hs
		915391 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTA_HUMAN (2-389): 0: 558: 45.62
+	Hs
		930053 PACN2_HUMAN (131-591): 1.56e-44: 167: 15.48		ACTG_HUMAN (2-389): 0: 566: 46.13
+	Hs
		596210 NEBU_HUMAN (64-591): 6.24e-45: 174: 15.20		ACTH_HUMAN (2-389): 0: 556: 45.36
+	Hs
		896904 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ARP2_HUMAN (7-389): 0: 549: 67.89
+	Sp
		1358186 MYO1_SCHPO (8-588): 8.35e-31: 130: 11.67		ARP2_SCHPO (6-391): 0: 590: 72.80
+	Ce
		501469 Q9XUT0_CAEEL (6-591): 8.49e-38: 150: 17.56		ACT2_CAEEL (2-389): 0: 567: 46.13
+	Hs
		891757 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTB_HUMAN (2-389): 0: 566: 46.39
+	Hs
		929858 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTG_HUMAN (2-389): 0: 566: 46.13
+	Hs
		891762 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTB_HUMAN (2-389): 0: 566: 46.39
+	Hs
		929863 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTG_HUMAN (2-389): 0: 566: 46.13
+	Hs
		932976 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTS_HUMAN (2-389): 0: 559: 45.62
+	Hs
		932154 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTC_HUMAN (2-389): 0: 559: 45.88
+	Mm
		897016 SRC8_MOUSE (318-590): 9.52e-31: 128: 22.02		ARP2_MOUSE (7-389): 0: 549: 67.89
+	Hs
		896890 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ARP2_HUMAN (7-389): 0: 549: 67.89