HitPredict

Interactor 1: VPP2 (P15920)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Immune suppressor factor J6B7) (ISF) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (ShIF) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: Atp6v0a2

Interactor 2: CYH2 (P63034)
Cytohesin-2 (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2) (CLM2) (SEC7 homolog B) (mSec7-2)
Gene: Cyth2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	16415858
Identification Methods	pull down, anti bait coimmunoprecipitation, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 856 Mm			1 400
+	Hs
		1303455 VPP2_HUMAN (1-856): 0: 1315: 91.59		CYH2_HUMAN (1-400): 3.33e-180: 508: 99.25
+	Hs
		1274133 VPP1_HUMAN (1-842): 0: 1259: 52.36		CYH2_HUMAN (1-400): 3.33e-180: 508: 99.25
+	Hs
		1303450 VPP4_HUMAN (1-843): 0: 1231: 51.30		CYH2_HUMAN (1-400): 3.33e-180: 508: 99.25
+	Hs
		1035683 VPP3_HUMAN (1-843): 0: 1081: 50.82		CYH2_HUMAN (1-400): 3.33e-180: 508: 99.25