HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 538
+	Hs
		551766 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88
+	Hs
		551632 DESP_HUMAN (1-2871): 0: 818: 100.00		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		551854 DESP_HUMAN (1-2871): 0: 818: 100.00		NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38
+	Hs
		551723 DESP_HUMAN (1-2871): 0: 818: 100.00		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		551655 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		792973 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		234241 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88
+	Mm
		925837 Q155P7_MOUSE (23-636): 6.99e-16: 87.3: 7.13		LIS1_MOUSE (104-423): 6.46e-53: 186: 9.65
+	Hs
		1068625 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		903240 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		166777 CE290_HUMAN (30-867): 9.79e-15: 83.5: 8.20		WDR83_HUMAN (1-327): 4.72e-39: 146: 20.61
+	Hs
		885302 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR83_HUMAN (1-327): 4.72e-39: 146: 20.61
+	Hs
		903212 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		903233 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1281478 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		963378 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		885220 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		903137 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		903607 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41