HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: DCA10 (Q5QP82)
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)
Gene: DCAF10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 559
+	Hs
		551766 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5B_HUMAN (12-325): 5.26e-48: 171: 12.50
+	Hs
		551659 DESP_HUMAN (1-2871): 0: 818: 100.00		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		551655 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		551854 DESP_HUMAN (1-2871): 0: 818: 100.00		NLE1_HUMAN (390-556): 5.65e-18: 89: 13.30
+	Hs
		551632 DESP_HUMAN (1-2871): 0: 818: 100.00		LIS1_HUMAN (400-555): 6.63e-16: 81.7: 12.82
+	Hs
		551882 DESP_HUMAN (1-2871): 0: 818: 100.00		WSB1_HUMAN (171-322): 3.49e-13: 73.6: 22.56
+	Hs
		551858 DESP_HUMAN (1-2871): 0: 818: 100.00		WSB2_HUMAN (171-348): 7.11e-12: 69.4: 23.56
+	Hs
		234229 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		DCA10_HUMAN (1-559): 4.4e-96: 305: 100.00
+	Hs
		234241 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WDR5B_HUMAN (12-325): 5.26e-48: 171: 12.50
+	Hs
		903240 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		792973 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		LIS1_HUMAN (400-555): 6.63e-16: 81.7: 12.82
+	Hs
		903212 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		1313659 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		KTNB1_HUMAN (15-264): 2.16e-32: 133: 9.16
+	Hs
		903233 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		885225 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		885220 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Mm
		925837 Q155P7_MOUSE (23-636): 6.99e-16: 87.3: 7.13		LIS1_MOUSE (400-555): 5.58e-16: 82.1: 12.82
+	Hs
		903137 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		903607 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55