HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: AHI1 (Q8N157)
Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1)
Gene: AHI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2871 Hs			1 1196
+	Hs
		551632 DESP_HUMAN (1-2871): 0: 818: 100.00		LIS1_HUMAN (406-830): 3.67e-64: 225: 10.84
+	Hs
		551655 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5_HUMAN (731-1077): 1.07e-50: 184: 12.07
+	Hs
		551870 DESP_HUMAN (1-2871): 0: 818: 100.00		FBW1A_HUMAN (726-1062): 5.01e-40: 159: 8.96
+	Hs
		551723 DESP_HUMAN (1-2871): 0: 818: 100.00		SMU1_HUMAN (773-1103): 7.21e-37: 148: 11.34
+	Hs
		551766 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5B_HUMAN (461-725): 4.52e-33: 133: 15.50
+	Hs
		551858 DESP_HUMAN (1-2871): 0: 818: 100.00		WSB2_HUMAN (599-803): 2.41e-25: 112: 18.06
+	Hs
		551854 DESP_HUMAN (1-2871): 0: 818: 100.00		NLE1_HUMAN (432-639): 3.72e-13: 75.4: 10.58
+	Hs
		551747 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR82_HUMAN (614-906): 6.67e-12: 70.1: 25.33
+	Hs
		792973 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		LIS1_HUMAN (406-830): 3.67e-64: 225: 10.84
+	Mm
		1207822 PLEC_MOUSE (2027-2819): 5.76e-29: 130: 31.55		A16L1_MOUSE (582-897): 8.71e-64: 230: 21.30
+	Hs
		903240 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		WDR5_HUMAN (731-1077): 1.07e-50: 184: 12.07
+	Mm
		925837 Q155P7_MOUSE (23-636): 6.99e-16: 87.3: 7.13		LIS1_MOUSE (417-830): 1.21e-64: 227: 11.99
+	Hs
		903212 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		WDR5_HUMAN (731-1077): 1.07e-50: 184: 12.07
+	Hs
		903233 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		WDR5_HUMAN (731-1077): 1.07e-50: 184: 12.07
+	Hs
		1146799 CP250_HUMAN (1093-2582): 3.26e-49: 197: 10.07		A16L1_HUMAN (604-774): 4.19e-14: 79: 17.45
+	Hs
		234241 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WDR5B_HUMAN (461-725): 4.52e-33: 133: 15.50
+	Hs
		885220 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR5_HUMAN (731-1077): 1.07e-50: 184: 12.07
+	Hs
		1068564 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		A16L1_HUMAN (604-774): 4.19e-14: 79: 17.45
+	Hs
		166777 CE290_HUMAN (30-867): 9.79e-15: 83.5: 8.20		WDR83_HUMAN (579-870): 3.98e-42: 159: 14.33
+	Hs
		1059230 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		A16L1_HUMAN (604-774): 4.19e-14: 79: 17.45