HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: WRP73 (Q9P2S5)
WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)
Gene: WRAP73

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26545777
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 460
+	Hs
		551655 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		551766 DESP_HUMAN (1-2871): 0: 818: 100.00		WDR5B_HUMAN (270-456): 2.27e-41: 151: 15.51
+	Hs
		551632 DESP_HUMAN (1-2871): 0: 818: 100.00		LIS1_HUMAN (275-459): 3.43e-39: 147: 9.73
+	Hs
		551854 DESP_HUMAN (1-2871): 0: 818: 100.00		NLE1_HUMAN (1-76): 3.09e-15: 79.8: 17.95
+	Hs
		234300 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WRP73_HUMAN (1-460): 4.09e-100: 308: 100.00
+	Hs
		166794 CE290_HUMAN (30-867): 9.79e-15: 83.5: 8.20		WRP73_HUMAN (1-460): 4.09e-100: 308: 100.00
+	Hs
		885325 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WRP73_HUMAN (1-460): 4.09e-100: 308: 100.00
+	Hs
		903240 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		792973 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		LIS1_HUMAN (275-459): 3.43e-39: 147: 9.73
+	Hs
		197084 CP250_HUMAN (1093-2582): 3.26e-49: 197: 10.07		PRP4_HUMAN (50-360): 9.05e-22: 99: 13.75
+	Hs
		903212 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		234241 PEPL_HUMAN (1428-2565): 6.62e-28: 126: 14.08		WDR5B_HUMAN (270-456): 2.27e-41: 151: 15.51
+	Hs
		903233 GOGB1_HUMAN (1530-2529): 4.77e-20: 101: 9.08		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Mm
		925837 Q155P7_MOUSE (23-636): 6.99e-16: 87.3: 7.13		LIS1_MOUSE (275-459): 2.77e-39: 148: 9.73
+	Hs
		885220 EPIPL_HUMAN (2574-2832): 1.51e-11: 73.1: 15.71		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		903137 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		903607 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		1313659 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		KTNB1_HUMAN (8-171): 3.12e-13: 73.7: 18.08