HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	37827155, 21145461
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 768
+	Hs
		552675 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		552676 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		552672 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		552673 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		553360 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77