HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: MED1 (Q15648)
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Gene: MED1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	30217970, 37827155
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 1581
+	Hs
		552728 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		552957 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		553224 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2C_HUMAN (1092-1565): 3.68e-11: 70.9: 12.71
+	Hs
		553011 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43