HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: EDC4 (Q6P2E9)
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Gene: EDC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 1401
+	Hs
		1026447 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		EDC4_HUMAN (1-1401): 0: 1319: 100.00
+	Hs
		554062 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MACF1_HUMAN (908-1276): 1.45e-46: 186: 10.59
+	Hs
		552539 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		DYST_HUMAN (950-1290): 2.23e-12: 74.4: 11.29
+	Hs
		553011 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SRCAP_HUMAN (542-990): 5.81e-12: 73.2: 12.05
+	Hs
		553449 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91
+	Hs
		553224 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2C_HUMAN (433-1018): 2.98e-10: 67.5: 10.44
+	Hs
		553336 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CBP_HUMAN (423-883): 7.13e-10: 66.3: 11.91
+	Hs
		551908 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SON_HUMAN (426-1085): 5.29e-09: 63.2: 11.38
+	Hs
		974062 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		DYST_HUMAN (950-1290): 2.23e-12: 74.4: 11.29
+	Hs
		1026512 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91
+	Hs
		577630 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		SON_HUMAN (426-1085): 5.29e-09: 63.2: 11.38