HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: CHD1L (Q86WJ1)
Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) (Amplified in liver cancer protein 1)
Gene: CHD1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	37827155, 19666485, 19661379
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035861 - site of double-strand break
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 897
+	Hs
		553774 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CHD8_HUMAN (1-856): 0: 643: 27.69
+	Hs
		229295 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA5_HUMAN (9-786): 0: 603: 32.60
+	Hs
		552009 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA1_HUMAN (35-786): 0: 594: 32.63
+	Hs
		552742 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CHD4_HUMAN (18-775): 0: 584: 32.19
+	Hs
		552270 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA4_HUMAN (3-782): 0: 567: 29.03
+	Hs
		552269 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA2_HUMAN (3-782): 8.8e-177: 555: 28.77
+	Hs
		151376 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CHD1_HUMAN (40-526): 5.8e-112: 379: 45.51