HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: SPDLY (Q96EA4)
Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1)
Gene: SPDL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 605
+	Hs
		554170 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MRCKB_HUMAN (5-542): 2e-75: 264: 18.02
+	Hs
		1026507 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		551597 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		254444 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		ROCK2_HUMAN (2-601): 2.07e-45: 175: 18.70
+	Hs
		552079 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		552080 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		552089 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MYH11_HUMAN (14-535): 3.32e-14: 78.3: 12.27
+	Hs
		553324 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03