Interactor 1: PRP16 (P15938)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13)
Gene: PRP16

Interactor 2: PRP22 (P24384)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 (EC 3.6.4.13)
Gene: PRP22

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 11290703, 20089683
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2, DEAD~Helicase_C, HA2~Helicase_C, HA2~OB_NTP_bind, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, OB_NTP_bind~OB_NTP_bind
Common GO terms GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0016887 - ATP hydrolysis activity
GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1071
Sc

1 1145
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024