HitPredict

Interactor 1: MUC1 (P15941)
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
Gene: MUC1

Interactor 2: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	24043631
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 345
+	Hs
		569419 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		570188 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		831120 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Rn
		94372 F1M9G7_RAT (29-1028): 5.45e-21: 102: 12.12		CEBPB_RAT (1-345): 2.12e-49: 169: 64.35
+	Hs
		831329 NCOA6_HUMAN (10-1050): 3.47e-16: 86.7: 9.70		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831618 MINT_HUMAN (22-1062): 3.99e-14: 80.1: 9.50		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		131703 BCL9_HUMAN (150-1126): 4.42e-13: 76.3: 8.09		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		146181 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831502 KMT2C_HUMAN (3-610): 1.39e-10: 68.3: 12.67		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		547800 NCOA6_HUMAN (10-1050): 3.47e-16: 86.7: 9.70		ATF2_HUMAN (49-342): 3.06e-41: 152: 17.63
+	Hs
		831810 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831744 BICRA_HUMAN (23-1109): 2.84e-09: 63.9: 11.04		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		152613 KMT2D_HUMAN (572-1064): 9.35e-09: 62.4: 12.35		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831924 MINT_HUMAN (22-1062): 3.99e-14: 80.1: 9.50		CEBPD_HUMAN (46-344): 1.55e-36: 134: 28.43
+	Hs
		146166 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		DDIT3_HUMAN (213-332): 7.77e-24: 97.9: 20.33
+	Dm
		1370284 Q9VLS7_DROME (4-946): 1.2e-18: 94.7: 11.85		Q9VTE8_DROME (251-333): 2.61e-15: 73.2: 27.06