HitPredict

Interactor 1: MUC1 (P15941)
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
Gene: MUC1

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	9819408, 11152665
Identification Methods	pull down, affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 420
+	Hs
		835988 TARA_HUMAN (36-1064): 2.31e-23: 110: 8.69		GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00
+	Hs
		625250 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70
+	Dm
		54307 A1Z9J3_DROME (31-566): 5.35e-17: 89.5: 14.02		SGG_DROME (1-393): 8.87e-144: 421: 77.16
+	Dm
		113978 M9PB30_DROME (4-533): 3.28e-15: 83.6: 13.22		SGG_DROME (1-393): 8.87e-144: 421: 77.16
+	Hs
		835573 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75
+	Hs
		625642 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70
+	Hs
		841300 MINT_HUMAN (22-1062): 3.99e-14: 80.1: 9.50		CDK7_HUMAN (56-374): 2.6e-51: 177: 36.61