HitPredict

Interactor 1: MUC1 (P15941)
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
Gene: MUC1

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22869720
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0002039 - p53 binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 826
+	Hs
		848230 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Rn
		193481 CBP_RAT (29-1028): 9.13e-21: 101: 12.02		HIF1A_RAT (1-826): 0: 714: 89.40
+	Hs
		971082 MUC3A_HUMAN (11-1015): 7.71e-10: 66.1: 11.58		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		1057760 NCOA6_HUMAN (10-1050): 3.47e-16: 86.7: 9.70		NCOA2_HUMAN (1-747): 3.97e-109: 367: 15.62
+	Ce
		108089 UNC89_CAEEL (19-476): 7.05e-17: 89.2: 8.39		HIF1_CAEEL (8-535): 5.37e-95: 314: 23.28