Interactor 1: GATA1 (P15976)
Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein)
Gene: GATA1

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.569

The method score is based on:

Property Details
Experiments 16107690
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0043066 - negative regulation of apoptotic process
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 413
Hs

1 480
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024