Interactor 1: GATA1 (P15976)
Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein)
Gene: GATA1

Interactor 2: PIAS4 (Q8N2W9)
E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
Gene: PIAS4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 16371476, 32814053
Identification Methods enzymatic study, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008270 - zinc ion binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 413
Hs

1 510
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024