HitPredict

Interactor 1: DCR2 (A1ZAW0)
Endoribonuclease Dcr-2 (Protein Dicer-2) (EC 3.1.26.3)
Gene: Dcr-2

Interactor 2: DCR2 (A1ZAW0)
Endoribonuclease Dcr-2 (Protein Dicer-2) (EC 3.1.26.3)
Gene: Dcr-2

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26257286
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Dicer_dimer, DEAD~Helicase_C, DEAD~Ribonuclease_3, Dicer_dimer~Ribonuclease_3, dsrm~dsrm, Helicase_C~dsrm, Ribonuclease_3~dsrm, Helicase_C~Helicase_C, PAZ~PAZ, PAZ~Ribonuclease_3, Ribonuclease_3~Ribonuclease_3
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0004386 - helicase activity
GO:0004525 - ribonuclease III activity
and 27 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1722
Dm

1 1722
+ At
+ At
+ Hs
+ Mm
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024