HitPredict

Interactor 1: KPCE (P16054)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: Prkce

Interactor 2: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	10862698
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0016020 - membrane GO:0043278 - response to morphine and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 737 Mm			1 938
+	Mm
		723567 KPCB_MOUSE (137-736): 0: 617: 44.53		NMDZ1_MOUSE (1-938): 0: 920: 100.00
+	Hs
		566366 KPCA_HUMAN (137-736): 0: 617: 45.17		NMDZ1_HUMAN (1-938): 0: 914: 99.04
+	Mm
		554900 KPCE_MOUSE (1-737): 0: 883: 100.00		NMDE2_MOUSE (4-938): 0: 628: 23.86
+	Mm
		723561 KPCG_MOUSE (156-736): 0: 573: 42.65		NMDZ1_MOUSE (1-938): 0: 920: 100.00
+	Hs
		566316 KPCA_HUMAN (137-736): 0: 617: 45.17		GRIA1_HUMAN (5-904): 0: 680: 21.77
+	Hs
		566381 KPCA_HUMAN (137-736): 0: 617: 45.17		NMDE2_HUMAN (4-938): 0: 634: 24.07
+	Mm
		934622 KPCB_MOUSE (137-736): 0: 617: 44.53		NMDE2_MOUSE (4-938): 0: 628: 23.86
+	Hs
		397148 KPCG_HUMAN (156-736): 0: 575: 42.79		GRIA4_HUMAN (7-888): 0: 659: 21.72
+	Mm
		930563 KPCG_MOUSE (156-736): 0: 573: 42.65		NMDE2_MOUSE (4-938): 0: 628: 23.86
+	Mm
		620958 AKT2_MOUSE (289-732): 4.9e-154: 457: 35.89		GRIA2_MOUSE (3-856): 0: 628: 21.55
+	Hs
		681815 AKT1_HUMAN (289-732): 2.76e-153: 456: 36.18		NMDE1_HUMAN (1-923): 0: 623: 24.11
+	Rn
		94346 KPCI_RAT (91-248): 2.44e-35: 144: 25.46		GRIA1_RAT (5-904): 0: 672: 21.64