Interactor 1: KPCE (P16054)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: Prkce

Interactor 2: MK03 (Q63844)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 11139474
Identification Methods coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0000165 - MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 8 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 737
Mm

1 380
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024