HitPredict

Interactor 1: MET (P16056)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	27086544
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1379 Mm			1 245
+	Hs
		441479 MET_HUMAN (1-1379): 0: 1320: 89.36		1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59
+	Mm
		554970 MET_MOUSE (1-1379): 0: 1369: 100.00		1433G_MOUSE (1-240): 8.4e-109: 315: 74.59
+	Hs
		441444 MET_HUMAN (1-1379): 0: 1320: 89.36		1433S_HUMAN (1-237): 2.52e-103: 301: 71.55
+	Hs
		926953 RON_HUMAN (23-1371): 0: 956: 33.19		1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59
+	Hs
		909466 RON_HUMAN (23-1371): 0: 956: 33.19		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		646822 RON_HUMAN (23-1371): 0: 956: 33.19		1433T_HUMAN (1-245): 2.6e-140: 395: 80.00
+	Hs
		683284 RON_HUMAN (23-1371): 0: 956: 33.19		1433B_HUMAN (1-242): 9.01e-140: 393: 88.02
+	Hs
		904469 RON_HUMAN (23-1371): 0: 956: 33.19		1433G_HUMAN (1-240): 8.4e-109: 315: 74.59
+	Hs
		981860 RON_HUMAN (23-1371): 0: 956: 33.19		1433F_HUMAN (2-240): 5.21e-108: 313: 74.49
+	Hs
		683980 RON_HUMAN (23-1371): 0: 956: 33.19		1433S_HUMAN (1-237): 2.52e-103: 301: 71.55
+	At
		1277300 SERK1_ARATH (803-1365): 2.99e-141: 447: 19.05		14337_ARATH (2-238): 9.2e-142: 399: 62.24
+	At
		965320 BAK1_ARATH (774-1364): 1.81e-138: 439: 18.54		14332_ARATH (3-239): 6.89e-143: 401: 65.15
+	At
		965327 PBS1_ARATH (994-1340): 6.31e-117: 375: 24.46		14332_ARATH (3-239): 6.89e-143: 401: 65.15
+	Hs
		609187 FGFR3_HUMAN (980-1358): 4.65e-105: 354: 32.08		1433B_HUMAN (1-242): 9.01e-140: 393: 88.02
+	Hs
		909494 MERTK_HUMAN (1055-1374): 6.94e-68: 251: 41.84		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		674386 UFO_HUMAN (1076-1331): 8.43e-66: 243: 45.90		1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59
+	Hs
		646846 MERTK_HUMAN (1055-1374): 6.94e-68: 251: 41.84		1433T_HUMAN (1-245): 2.6e-140: 395: 80.00
+	Hs
		683304 MERTK_HUMAN (1055-1374): 6.94e-68: 251: 41.84		1433B_HUMAN (1-242): 9.01e-140: 393: 88.02
+	Hs
		674348 UFO_HUMAN (1076-1331): 8.43e-66: 243: 45.90		1433B_HUMAN (1-242): 9.01e-140: 393: 88.02
+	Hs
		435542 IGF1R_HUMAN (1082-1335): 7.57e-57: 218: 42.16		1433T_HUMAN (1-245): 2.6e-140: 395: 80.00