HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005902 - microvillus GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 1089
+	Hs
		555076 CD44_HUMAN (1-742): 0: 610: 100.00		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		555078 CD44_HUMAN (1-742): 0: 610: 100.00		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		555083 CD44_HUMAN (1-742): 0: 610: 100.00		UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71
+	Hs
		507830 CD44_HUMAN (1-742): 0: 610: 100.00		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Dr
		60057 A4JYN2_DANRE (8-643): 1.08e-109: 364: 16.16		VGFR4_DANRE (110-787): 8.42e-39: 159: 11.55
+	Hs
		508148 PGCB_HUMAN (13-491): 2.84e-100: 331: 15.24		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71