HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0030667 - secretory granule membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 250
+	Hs
		449175 CD44_HUMAN (1-742): 0: 610: 100.00		LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00
+	Hs
		119143 CD44_HUMAN (1-742): 0: 610: 100.00		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		121100 CD44_HUMAN (1-742): 0: 610: 100.00		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Mm
		139221 CD44_MOUSE (1-742): 0: 540: 65.90		LEG9_MOUSE (108-249): 6.6e-40: 142: 38.62
+	Hs
		530369 CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86		LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04
+	Hs
		449171 CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86		LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00