HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 192
+	Hs
		555121 CD44_HUMAN (1-742): 0: 610: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545194 CD44_HUMAN (1-742): 0: 610: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		555194 CD44_HUMAN (1-742): 0: 610: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		555124 CD44_HUMAN (1-742): 0: 610: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		555111 CD44_HUMAN (1-742): 0: 610: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		555115 CD44_HUMAN (1-742): 0: 610: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436144 CD44_HUMAN (1-742): 0: 610: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		555068 CD44_HUMAN (1-742): 0: 610: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		297823 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		297812 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		297840 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		297819 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		297827 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		297820 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		297809 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79