HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 196
+	Hs
		555121 CD44_HUMAN (1-742): 0: 610: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		555115 CD44_HUMAN (1-742): 0: 610: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545194 CD44_HUMAN (1-742): 0: 610: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436144 CD44_HUMAN (1-742): 0: 610: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		555124 CD44_HUMAN (1-742): 0: 610: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		555110 CD44_HUMAN (1-742): 0: 610: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		555111 CD44_HUMAN (1-742): 0: 610: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		555068 CD44_HUMAN (1-742): 0: 610: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120296 CD44_HUMAN (1-742): 0: 610: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		297823 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		297820 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		297822 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		297812 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		297809 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		297827 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		297819 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		120250 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98