HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0042995 - cell projection
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 258
+	Hs
		436144 CD44_HUMAN (1-742): 0: 610: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		555179 CD44_HUMAN (1-742): 0: 610: 100.00		RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66
+	Hs
		555110 CD44_HUMAN (1-742): 0: 610: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		555124 CD44_HUMAN (1-742): 0: 610: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		555121 CD44_HUMAN (1-742): 0: 610: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		555119 CD44_HUMAN (1-742): 0: 610: 100.00		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		555115 CD44_HUMAN (1-742): 0: 610: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545194 CD44_HUMAN (1-742): 0: 610: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		555111 CD44_HUMAN (1-742): 0: 610: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		555068 CD44_HUMAN (1-742): 0: 610: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		555194 CD44_HUMAN (1-742): 0: 610: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26
+	Hs
		297809 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		297834 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00
+	Hs
		297819 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		297827 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		297823 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		297820 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		297812 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		297840 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26