Interactor 1: SPTN1 (P16086)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: ACTN1 (Q9Z1P2)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11274145
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EF-hand_7, EF-hand_6~EF-hand_7, EF-hand_7~EFhand_Ca_insen, CH~EFhand_Ca_insen, EFhand_Ca_insen~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin
Common GO terms GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005916 - fascia adherens
GO:0030018 - Z disc
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2472
Rn

1 892
+ Hs
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+ Dm
+ Dm
+ Hs
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+ Ce
+ Hs
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+ Rn
+ Ce
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+ Dm
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+ Mm

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Last updated: 15 Jul 2024