Interactor 1: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50

Interactor 2: COM1 (P46946)
DNA endonuclease SAE2 (EC 3.1.-.-) (Completion of meiotic recombination protein 1) (Sporulation in the absence of SPO11 protein 2)
Gene: SAE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.55 0.698

The method score is based on:

Property Details
Experiments 25231868, 30275497, 39174552, 35429499, 35501303, 39558159
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0003690 - double-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030870 - Mre11 complex
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025