HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007283 - spermatogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 372
+	Hs
		391536 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00
+	Hs
		470256 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00
+	Hs
		563114 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00
+	Hs
		555408 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		555702 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54
+	Hs
		391647 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		470334 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		931186 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Hs
		1216285 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54
+	Hs
		470618 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54
+	Hs
		1087142 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54
+	Hs
		555650 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		1307112 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		1296212 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		1151383 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		470564 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		594868 H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		1087105 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82
+	Hs
		1312231 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82